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[DOI] [PMC free article] [PubMed] [Google Scholar] Liu J, Conde K, Zhang P, Lilascharoen V, Xu Z, Lim BK, Seeley RJ, Zhu JJ, Scott MM, Pang ZP, 2017
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5 Mechanisms by which metformin acts through regulation of the gut microbiota 5.1 Acts by stabilizing the mucosal barrier of the GI tract The GI mucosal barrier with important physiological roles is a three-dimensional protective structure consisting of mechanical, chemical, immune and biological barriers